Acute Toxicity is a term used in toxicology to describe the immediate harmful effects of a substance or chemical on living organisms, typically resulting from a single exposure or short-term exposure. It refers to the ability of a substance to cause severe adverse effects, such as illness, injury, or death, when it is absorbed, inhaled, ingested, or comes into contact with the skin or eyes. The severity of acute toxicity is often measured by the lethal dose (LD50), which indicates the amount of a substance required to cause death in 50% of the test population within a specified time frame. Acute toxicity is an important consideration in the assessment of the safety and potential hazards of various substances, including pharmaceutical drugs, pesticides, industrial chemicals, and household products.
Acute toxicity refers to the ability of a substance to cause harmful effects on an organism after a single or short-term exposure. It is a crucial aspect of chemical safety assessment and is often evaluated to determine the potential risks associated with a particular substance. Acute toxicity studies involve administering the substance to test animals and observing any adverse effects, such as death, organ damage, or behavioural changes. The results are then used to establish dose-response relationships and determine the lethal dose (LD50) or concentration (LC50) that causes toxicity in 50% of the test population. This information helps regulatory authorities set exposure limits and develop safety guidelines to protect human health and the environment.
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This glossary post was last updated: 29th March 2024.
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